Proteomics

Key advantages

• High-throughput identification and quantification of thousands of proteins

• Supports label-free and multiplexed labeling techniques (TMT, iTRAQ)

• Enables discovery of post-translational modifications (phosphorylation, ubiquitination, acetylation)

• Applicable to diverse sample types: tissues, cells, biofluids

• Facilitates biomarker discovery, drug target validation, and functional pathway analysis

• Integration with genomic and transcriptomic data for comprehensive multi-omics insights

• Robust workflows for clinical, translational, and basic research

• Advanced bioinformatics for protein identification, quantitation, and network analysis

Technical specifications

• Mass spectrometry platforms: Thermo Scientific Orbitrap, Q Exactive, and SCIEX TripleTOF

• Sample preparation: protein extraction, digestion (trypsin), fractionation

• Quantification methods: label-free quantitation, TMT/iTRAQ multiplexing

• Data acquisition modes: DDA (Data-Dependent Acquisition), DIA (Data-Independent Acquisition)

• Output files: raw MS data, peptide/protein identification (mzML, mzXML), quantitation tables

• Bioinformatics pipeline: peptide-spectrum matching, FDR control, PTM analysis, pathway enrichment

• Optional analyses: targeted proteomics (PRM, SRM), protein interaction mapping

• Secure data storage and visualization with interactive dashboards and reports